Resmetirom
Resmetirom (MGL-3196) is an orally active, highly selective thyroid hormone receptor-beta (THR-β) agonist with an EC50 of 0.21 μM. It is a research compound used in studies of non-alcoholic steatohepatitis (NASH), with applications in both in vitro mechanistic studies and in vivo models of liver disease.
Product Specifications
CAS Number
920509-32-6
Product Name Alternative
Inhibitor, MGL3196, MGL-3196, MGL 3196, inhibit, VIA 3196, VIA3196, VIA-3196, Resmetirom, THR-β, THR, Thyroidhormonereceptor, Thyroidhormonereceptor (THR), Thyroid hormone receptor (THR), Thyroid Hormone Receptor, Thyroid hormone receptor
Field of Research
Metabolism Research
Purity
99.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.58 mM) ; DMSO:101 mg/mL (232.07 mM)
Smiles
CC (C) c1cc (Oc2c (Cl) cc (cc2Cl) -n2nc (C#N) c (=O) [nH]c2=O) n[nH]c1=O
Molecular Formula
C17H12Cl2N6O4
Molecular Weight
435.22
Storage Conditions
-20°C
Notes
For research use only.
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