PD-325901
Mirdametinib (PD325901) is a potent, selective, and orally active non-ATP-competitive MEK inhibitor (IC50=0.33 nM) . It demonstrates antitumor activity in research models by suppressing p-ERK1/2 and promoting apoptosis, making it a valuable tool for studying MAPK/ERK pathway dysregulation in cancer, both in vitro and in vivo.
Product Specifications
CAS Number
391210-10-9
Product Name Alternative
Autophagy, Apoptosis, inhibit, Mitogen-activated protein kinase kinase, Mirdametinib, PD325901, PD-325901, PD0325901, PD-0325901, PD 0325901, PD 325901, Inhibitor, MAP2K, MAPKK, MEK
Field of Research
Stem Cell & Developmental Biology
Purity
> 98%
Bioactivity
MEK inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 12 mg/ml)
Smiles
OC[C@@H] (O) CONC (=O) C1=CC=C (F) C (F) =C1NC1=CC=C (I) C=C1F
Molecular Formula
C16H14F3IN2O4
Molecular Weight
482.20
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-[ (2R) -2,3-Dihydroxypropoxy]-3,4-difluoro-2-[ (2-fluoro-4-iodophenyl) amino]-benzamide
Available Sizes
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