PP1
PP1 (AGL 1872) is a potent and selective Src family kinase inhibitor, exhibiting IC50 values of 5 nM for Lck and 6 nM for Fyn. This cell-permeable compound is widely used in biochemical and cellular research to investigate T-cell receptor signaling and oncogenic pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
172889-26-8
Product Name Alternative
CKit, Apoptosis, Bcr-Abl, BcrAbl, AGL1872, AGL-1872, AGL 1872, Lck, Inhibitor, EI 275, EI275, EI-275, EGFR, Fyn, inhibit, Kit, Src, PP 1, PP1, PP-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
>98%
Bioactivity
Src family kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 10 mg/ml) .
Smiles
NC1=C2C (=NN (C (C) (C) C) C2=NC=N1) C3=CC=C (C) C=C3
Molecular Formula
C16H19N5
Molecular Weight
281.63
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-amino-1-tert-butyl-3- (4-methylphenyl) pyrazolo[3,4-d]pyrimidine
Available Sizes
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