DAPT
DAPT (LY-374973) is an orally bioavailable γ-secretase inhibitor that reduces total Aβ and Aβ42 production (IC50=115/200 nM) and inhibits Notch signaling. This small molecule is used in research to study Alzheimer's disease pathways and cellular processes like differentiation, autophagy, and apoptosis in both in vitro and in vivo models.
Product Specifications
CAS Number
208255-80-5
Product Name Alternative
LY-374973
Field of Research
Cancer Biology, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
G-secretase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
C[C@H] (NC (=O) Cc1cc (F) cc (F) c1) C (=O) N[C@H] (C (=O) OC (C) (C) C) c1ccccc1
Molecular Formula
C23H26F2N2O4
Molecular Weight
432.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[N- (3,5-Difluorophenacetyl) -L-alanyl]-S-phenylglycine t-butyl ester
Available Sizes
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