Saxagliptin
Saxagliptin (BMS-477118) is a potent, reversible, and selective DPP-4 inhibitor exhibiting an IC50 of 26 nM. It is widely used in diabetes research to study glycemic control mechanisms in both cellular assays and animal models of type 2 diabetes.
Product Specifications
CAS Number
361442-04-8
Product Name Alternative
C-myc, diabetes, Dipeptidyl Peptidase, DPP, DPP4, DPP-4, BMS 477118, BMS477118, BMS-477118, Inhibitor, p-AKT, inhibit, Onglyza, insulin, glucagon-like, glucagon, β-catenin, Saxagliptin, proliferation, peptide-1
Field of Research
Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.05% (May vary between batches)
Solubility
H2O:58 mg/mL (183.89 mM) ; DMSO:35 mg/mL (110.97 mM) ; Ethanol:23 mg/mL (72.92 mM)
Smiles
[H][C@@]12C[C@]1 ([H]) N ([C@@H] (C2) C#N) C (=O) [C@@H] (N) [C@]12C[C@@]3 ([H]) C[C@] ([H]) (C[C@] (O) (C3) C1) C2
Molecular Formula
C18H25N3O2
Molecular Weight
315.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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