QNZ
QNZ (EVP4593) is a potent small molecule inhibitor of NF-κB activation and TNF-α production, with respective IC50 values of 11 nM and 7 nM. It is widely used in research to study inflammatory signaling pathways and has been applied in both cellular and animal models of inflammation and autoimmune disease.
Product Specifications
CAS Number
545380-34-5
Product Name Alternative
EVP4593
Field of Research
Neuroscience
Purity
>98%
Bioactivity
NFkB inhibitor / Store-operated calcium entry
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
Nc1ccc2ncnc (NCCc3ccc (Oc4ccccc4) cc3) c2c1
Molecular Formula
C22H20N4O
Molecular Weight
356.42
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-N-[2- (4-Phenoxyphenyl) ethyl]quinazoline-4,6-diamine
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