PHA-767491
PHA-767491 is a potent, ATP-competitive dual inhibitor of Cdc7 and CDK9 kinases, exhibiting IC50 values of 10 nM and 34 nM, respectively. It is widely used in biochemical and cellular research to investigate DNA replication stress, transcription, and oncology-related pathways in both in vitro and in vivo models.
Product Specifications
CAS Number
845714-00-3
Product Name Alternative
Cyclin dependent kinase, CAY10572, CAY-10572, CAY 10572, Cdc7, CDK1, CDK, CDK2, CDK9, inhibit, GSK3, GSK-3β, Inhibitor, PHA767491, PHA-767491, PHA 767491
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.42% (May vary between batches)
Solubility
DMSO:40 mg/mL (187.58 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C1C=2C=C (NC2CCN1) C=3C=CN=CC3
Molecular Formula
C12H11N3O
Molecular Weight
213.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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