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SC144

SC144 is a potent, orally bioavailable small molecule that selectively inhibits gp130 signaling. It has demonstrated efficacy in reducing tumor growth in vivo and is widely used in cancer research, particularly for studying IL-6/JAK/STAT3 pathways in both cellular and animal models.

Product Specifications

CAS Number

895158-95-9

Product Name Alternative

Inhibit, nuclear, oral, ovarian, Inhibitor, Interleukin Related, Interleukin, gp130, cancer, arrest, anti-angiogenesis, Apoptosis, cell-cycle, phosphorylation, SC144, SC-144, SC 144, translocation

Field of Research

Cell Biology, Immunology & Inflammation

Purity

99.20% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:15 mg/mL (46.54 mM)

Smiles

Cl.Fc1ccc2c (c1) nc (NNC (=O) c1cnccn1) c1cccn21

Molecular Formula

C16H11FN6O

Molecular Weight

322.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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