CW-069
CW-069 is a potent and selective allosteric inhibitor of the HSET (KIFC1) microtubule motor protein, with an IC50 of 75 μM. It demonstrates high specificity over the related kinesin KSP and is a valuable chemical probe for studying HSET function in cancer cell division and aneuploidy research in vitro.
Product Specifications
CAS Number
1594094-64-0
Product Name Alternative
Inhibitor, HSET, inhibit, Kinesin, Microtubule Associated, MicrotubuleAssociated, CW-069, CW 069, CW069
Field of Research
Signal Transduction
Purity
97.52% (May vary between batches)
Solubility
Ethanol:4 mg/mL (7.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.6 mM) ; DMSO:93 mg/mL (185.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) c1cc (I) ccc1NC (=O) [C@H] (Cc1ccccc1) NCc1ccccc1
Molecular Formula
C23H21IN2O3
Molecular Weight
500.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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