Vinorelbine ditartrate
Vinorelbine ditartrate (KW-2307) is a semi-synthetic vinca alkaloid that acts as an anti-mitotic agent, disrupting microtubule dynamics to inhibit tumor cell proliferation and induce apoptosis. It is widely used in cancer research, demonstrating activity in both in vitro cytotoxicity assays and in vivo xenograft models for various malignancies.
Product Specifications
CAS Number
125317-39-7
Product Name Alternative
Autophagy, inhibit, Inhibitor, Nor-5'-anhydrovinblastine, Nor-5'-anhydrovinblastine ditartrate, Nor-5'-anhydrovinblastine Ditartrate, KW2307, KW-2307, KW 2307, Microtubule/Tubulin, MicrotubuleAssociated, Microtubule Associated, Navelbine tartrate, Navelbine Tartrate, Tubulin, Vinorelbine, Vinorelbine ditartrate, Vinorelbine Ditartrate, Vinorelbine Tartrate
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
H2O:107.9 mg/mL (99.99 mM) ; DMSO:127 mg/mL (117.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (4.63 mM)
Smiles
O[C@H] ([C@@H] (O) C (O) =O) C (O) =O.O[C@H] ([C@@H] (O) C (O) =O) C (O) =O.CCC1=CC2CN (C1) Cc1c ([nH]c3ccccc13) [C@@] (C2) (C (=O) OC) c1cc2c (cc1OC) N (C) [C@@H]1[C@]22CCN3CC=C[C@] (CC) ([C@@H]23) [C@@H] (OC (C) =O) [C@]1 (O) C (=O) OC
Molecular Formula
C45H54N4O8·2C4H6O6
Molecular Weight
1079.11
Storage Conditions
-20°C
Notes
For research use only.
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