Irinotecan
Irinotecan (CPT-11) is a camptothecin-derived topoisomerase I inhibitor used in cancer research. It induces lethal double-strand DNA breaks by stabilizing the Topo I-DNA complex. This mechanism underpins its application in studying colorectal and other cancers in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
97682-44-5
Product Name Alternative
Inhibit, Inhibitor, Irinotecan, CPT 11, CPT11, CPT-11, Autophagy, (+) -Irinotecan, Topoisomerase, Topo I, Topotecin
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:11 mg/mL (18.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.2 mg/mL (5.45 mM)
Smiles
CCc1c2Cn3c (cc4c (COC (=O) [C@]4 (O) CC) c3=O) -c2nc2ccc (OC (=O) N3CCC (CC3) N3CCCCC3) cc12
Molecular Formula
C33H38N4O6
Molecular Weight
586.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Explore Other Products
Browse additional items from our catalog
Recombinant Borrelia garinii Basic membrane protein A1 (bmpA1)
Recombinant Borrelia garinii Basic membrane protein A1 (bmpA1)
Recombinant Borrelia garinii Basic membrane protein A1 (bmpA1)
Recombinant Borrelia garinii Basic membrane protein A1 (bmpA1)
Recombinant Borrelia garinii Basic membrane protein A1 (bmpA1)