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Daclatasvir

Daclatasvir (BMS-790052) is a potent and selective HCV NS5A inhibitor, demonstrating picomolar EC50 activity against multiple HCV genotypes in replicon assays and the infectious JFH-1 virus. Its efficacy, validated in both in vitro studies and pivotal Phase 3 clinical trials, makes it a critical tool for antiviral research targeting hepatitis C.

Product Specifications

CAS Number

1009119-64-5

Product Name Alternative

Daklinza, Daclatasvir, EBP 883, EBP883, EBP-883, antiviral, BMS790052, BMS-790052, BMS 790052, genotypes, Inhibitor, HCV Protease, HCVProtease, HCV, HCV NS5A, Hepatitis C virus, OATP1B1, OATP1B3, inhibit, NS5A, JFH-1, replicon

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.81% (May vary between batches)

Solubility

DMSO:136 mg/mL (184.06 mM) ; Ethanol:136 mg/mL (184.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.41 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

COC (=O) N[C@@H] (C (C) C) C (=O) N1CCC[C@H]1c1ncc ([nH]1) -c1ccc (cc1) -c1ccc (cc1) -c1cnc ([nH]1) [C@@H]1CCCN1C (=O) [C@@H] (NC (=O) OC) C (C) C

Molecular Formula

C40H50N8O6

Molecular Weight

738.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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