Daclatasvir
Daclatasvir (BMS-790052) is a potent and selective HCV NS5A inhibitor, demonstrating picomolar EC50 activity against multiple HCV genotypes in replicon assays and the infectious JFH-1 virus. Its efficacy, validated in both in vitro studies and pivotal Phase 3 clinical trials, makes it a critical tool for antiviral research targeting hepatitis C.
Product Specifications
CAS Number
1009119-64-5
Product Name Alternative
Daklinza, Daclatasvir, EBP 883, EBP883, EBP-883, antiviral, BMS790052, BMS-790052, BMS 790052, genotypes, Inhibitor, HCV Protease, HCVProtease, HCV, HCV NS5A, Hepatitis C virus, OATP1B1, OATP1B3, inhibit, NS5A, JFH-1, replicon
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.81% (May vary between batches)
Solubility
DMSO:136 mg/mL (184.06 mM) ; Ethanol:136 mg/mL (184.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.41 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COC (=O) N[C@@H] (C (C) C) C (=O) N1CCC[C@H]1c1ncc ([nH]1) -c1ccc (cc1) -c1ccc (cc1) -c1cnc ([nH]1) [C@@H]1CCCN1C (=O) [C@@H] (NC (=O) OC) C (C) C
Molecular Formula
C40H50N8O6
Molecular Weight
738.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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