Imatinib
Imatinib (STI571) is an orally active small molecule that potently and selectively inhibits the tyrosine kinases BCR-ABL, PDGFR, and c-Kit. It is widely used in research for chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GIST), and in vitro studies of oncogenic signaling pathways.
Product Specifications
CAS Number
152459-95-5
Product Name Alternative
Field of Research
Cardiovascular Research, Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.42% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.06 mM) ; DMSO:25 mg/mL (50.65 mM)
Smiles
CN1CCN (CC2=CC=C (C=C2) C (=O) NC2=CC (NC3=NC (=CC=N3) C3=CC=CN=C3) =C (C) C=C2) CC1
Molecular Formula
C29H31N7O
Molecular Weight
493.60
References & Citations
A Cama Fabio Verginelli, Silvia Perconti, Simone Vespa, Francesca Schiavi, Sampath Chandra Prasat, Paola Lanuti gruppootologico.com, (2024)
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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