Palbociclib Isethionate
Palbociclib Isethionate (PD 0332991 isethionate) is a potent and selective CDK4/6 inhibitor with IC50 values of 11 and 16 nM, respectively, and demonstrates high selectivity across kinases. It is widely used in cancer research, particularly for studying cell cycle arrest in breast cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
827022-33-3
Product Name Alternative
Inhibitor, inhibit, Palbociclib, Palbociclib (PD0332991) Isethionate, Palbociclib Isethionate, PD0332991, PD-0332991, PD 0332991, PD 0332991 isethionate, hepatocellular carcinoma, HER2, HCC, estrogen receptor, Cyclin dependent kinase, Breast cancer, CDK6/CyclinD2, CDK, CDK4/CyclinD1, CDK4/CyclinD3, cell cycle
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.01% (May vary between batches)
Solubility
DMSO:40 mg/mL (69.73 mM) ; H2O:57.4 mg/mL (100.06 mM)
Smiles
OCCS (O) (=O) =O.CC (=O) c1c (C) c2cnc (Nc3ccc (cn3) N3CCNCC3) nc2n (C2CCCC2) c1=O
Molecular Formula
C24H29N7O2·C2H6O4S
Molecular Weight
573.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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