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Rupatadine Fumarate

Rupatadine Fumarate (UR-12592 Fumarate) is a dual antagonist of platelet-activating factor (PAF) and the histamine H1 receptor, exhibiting high potency with respective Ki values of 0.55 μM and 0.1 μM. This small molecule is utilized in research to study allergic inflammation and anaphylaxis, with applications in both in vitro binding assays and in vivo models of allergic response.

Product Specifications

CAS Number

182349-12-8

Product Name Alternative

Rupafin, Rupatadine, Rupatadine Fumarate, rhinitis, Rinialer, urticaria, UR 12592, UR12592, UR-12592, Autophagy, Alergoliber, allergic, PAFR, PAF, Inhibitor, inhibit, Histamine Receptor, HistamineReceptor, H1 receptor

Field of Research

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

99.64% (May vary between batches)

Solubility

Ethanol:11 mg/mL (20.68 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.76 mM) ; DMSO:12 mg/mL (22.56 mM)

Smiles

OC (=O) \C=C\C (O) =O.Cc1cncc (CN2CC\C (CC2) =C2/c3ccc (Cl) cc3CCc3cccnc23) c1

Molecular Formula

C26H26ClN3·C4H4O4

Molecular Weight

532.03

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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