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AMG-208

AMG-208 is a potent and selective small molecule inhibitor of the c-Met receptor tyrosine kinase, exhibiting an IC50 of 9 nM. It has been utilized in preclinical research to investigate c-Met-driven tumorigenesis in both cellular assays and animal models, supporting its role in oncology research.

Product Specifications

CAS Number

1002304-34-8

Product Name Alternative

Inhibit, HGFR, Inhibitor, Cytochrome P450, CYPs, c-Met/HGFR, cMet, c-Met, cMet/HGFR, AMG 208, AMG208, AMG-208

Field of Research

Metabolism Research, Signal Transduction

Purity

98.56% (May vary between batches)

Solubility

DMSO:2.5 mg/mL (6.52 mM)

Smiles

COc1ccc2c (OCc3nnc4ccc (nn34) -c3ccccc3) ccnc2c1

Molecular Formula

C22H17N5O2

Molecular Weight

383.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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