AMG-208
AMG-208 is a potent and selective small molecule inhibitor of the c-Met receptor tyrosine kinase, exhibiting an IC50 of 9 nM. It has been utilized in preclinical research to investigate c-Met-driven tumorigenesis in both cellular assays and animal models, supporting its role in oncology research.
Product Specifications
CAS Number
1002304-34-8
Product Name Alternative
Inhibit, HGFR, Inhibitor, Cytochrome P450, CYPs, c-Met/HGFR, cMet, c-Met, cMet/HGFR, AMG 208, AMG208, AMG-208
Field of Research
Metabolism Research, Signal Transduction
Purity
98.56% (May vary between batches)
Solubility
DMSO:2.5 mg/mL (6.52 mM)
Smiles
COc1ccc2c (OCc3nnc4ccc (nn34) -c3ccccc3) ccnc2c1
Molecular Formula
C22H17N5O2
Molecular Weight
383.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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