Bosentan (hydrate)
Bosentan hydrate is a dual endothelin receptor antagonist that competitively inhibits both ET-A and ET-B receptors. It is widely used in research to study the role of endothelin-1 in cardiovascular diseases, pulmonary hypertension, and related pathways in both cellular and animal models.
Product Specifications
CAS Number
157212-55-0
Product Name Alternative
Ro 47-0203, Inhibitor, ET-B, ET-A, Endothelin Receptor, EndothelinReceptor, inhibit, Bosentan, Bosentan (hydrate), Bosentan Hydrate, Actelion, Benzenesulfonamide
Field of Research
Pharmacology & Drug Discovery
Purity
99.31% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (163.26 mM) ; Ethanol:2 mg/mL (3.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.79 mM)
Smiles
O.COC1=CC=CC=C1OC1=C (OCCO) N=C (N=C1NS (=O) (=O) C1=CC=C (C=C1) C (C) (C) C) C1=NC=CC=N1
Molecular Formula
C27H29N5O6S·H2O
Molecular Weight
569.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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