Fosbretabulin Disodium
Fosbretabulin Disodium is a water-soluble prodrug of Combretastatin A4 that acts as a microtubule-destabilizing agent by binding to β-tubulin. It inhibits tubulin polymerization and disrupts established tumor vasculature, making it a valuable compound for researching vascular-targeting therapies in oncology, both in vitro and in vivo.
Product Specifications
CAS Number
168555-66-6
Product Name Alternative
Combretastatin A4 disodium, Combretastatin A4 disodium phosphate, Combretastatin A4 disodium Phosphate, Combretastatin A4 Phosphate, destabilizing, CA 4DP, CA 4P, Apoptosis, Fosbretabulin, Fosbretabulin (Combretastatin A4 Phosphate (CA4P) ) Disodium, Fosbretabulin Disodium, endothelia, Inhibitor, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, neovessels, nascent, inhibit, Tubulin, tubulin, tumour
Field of Research
Cell Biology, Signal Transduction
Purity
97.43% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:10 mM
Smiles
[Na+].[Na+].COc1ccc (\C=C/c2cc (OC) c (OC) c (OC) c2) cc1OP ([O-]) ([O-]) =O
Molecular Formula
C18H19O8P·2Na
Molecular Weight
440.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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