Obatoclax (GX15-070)
Obatoclax Mesylate (GX15-070) is a small molecule Bcl-2 antagonist with a Ki of 0.22 μM. It induces apoptosis by upregulating Bim, promoting cytochrome c release, and activating caspase-3. This compound is utilized in cancer research for both in vitro studies and in vivo models to investigate mechanisms of programmed cell death.
Product Specifications
CAS Number
803712-79-0
Product Name Alternative
GX15-070
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Bcl-2 antagonist. Induces apoptosis
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) .
Smiles
CS (O) (=O) =O.COc1cc ([nH]c1=Cc1[nH]c (C) cc1C) =C1C=c2ccccc2=N1
Molecular Formula
C20H19N3O · CH3SO3H
Molecular Weight
413.50
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[2-[ (3,5-Dimethyl-1H-pyrrol-2-yl) methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
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