Sotrastaurin
Sotrastaurin (AEB071) is a highly potent and selective pan-PKC inhibitor, exhibiting sub-nanomolar to low nanomolar affinity for isoforms including PKCα, βI, δ, ε, η, and θ. It is widely used in research to investigate PKC signaling in immunology and oncology, with applications in both in vitro cellular assays and in vivo disease models.
Product Specifications
CAS Number
425637-18-9
Product Name Alternative
AEB071, AEB-071, AEB 071, inhibit, Inhibitor, PKCδ, PKCη, PKCθ, PKCβ1, PKCα, PKC, Protein kinase C, Sotrastaurin
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.53 mM) ; DMSO:81 mg/mL (184.73 mM) ; Ethanol:2 mg/mL (4.56 mM)
Smiles
CN1CCN (CC1) c1nc (C2=C (C (=O) NC2=O) c2c[nH]c3ccccc23) c2ccccc2n1
Molecular Formula
C25H22N6O2
Molecular Weight
438.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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