Givinostat hydrochloride
Givinostat hydrochloride (ITF2357 hydrochloride) is a histone deacetylase (HDAC) inhibitor with IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3. This small molecule demonstrates anti-inflammatory, anti-angiogenic, and antineoplastic properties, supporting its use in oncology and inflammation research in both cellular and animal models.
Product Specifications
CAS Number
199657-29-9
Product Name Alternative
ITF 2357 HCl, ITF2357 HCl, ITF-2357 HCl, ITF2357 hydrochloride, Givinostat HCl, HDAC1, HD2, HD1-A, HD1-B, HDAC10, HDAC11, HDAC2, HDAC6, HDAC3, HDAC4, HDAC5, HDAC9, HDAC7, HDAC8
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.01% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (60.05 mM)
Smiles
Cl.CCN (CC) Cc1ccc2cc (COC (=O) Nc3ccc (cc3) C (=O) NO) ccc2c1
Molecular Formula
C24H28ClN3O4
Molecular Weight
457.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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