NVP-BSK805 2HCl (1092499-93-8 (free base) )
NVP-BSK805 2HCl (1092499-93-8 free base) is a potent, ATP-competitive JAK2 inhibitor with an IC50 of 0.5 nM, demonstrating >20-fold selectivity over JAK1, JAK3, and TYK2. It is widely used in research to investigate JAK2-dependent signaling in cellular assays and hematological malignancy models.
Product Specifications
Product Name Alternative
Tyrosine Kinases, TyrosineKinases, Tyk2, BSK 805, BSK805, BSK-805, NVP BSK805 2HCl (1092499 93 8 (free base) ), NVP-BSK 805, NVP-BSK 805 Dihydrochloride, NVP-BSK805, NVP-BSK-805, NVP-BSK805 (dihydrochloride), NVPBSK805 2HCl (1092499938 (free base) ), NVP-BSK-805 2HCl (1092499-93-8 (free base) ), NVP-BSK805 2HCl (1092499-93-8 (free base) ), NVP-BSK805 dihydrochloride, NVP-BSK805 Dihydrochloride, NVP-BSK-805 Dihydrochloride, NVP-BSK805 2HCl (1092499-93-8 free base), JAK3, JAK2, JAK1
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.41% (May vary between batches)
Solubility
Ethanol:15 mg/mL (26.62 mM) ; H2O:3 mg/mL (5.32 mM) ; DMSO:113 mg/mL (200.54 mM)
Smiles
Cl.Cl.Fc1cc (cc (F) c1CN1CCOCC1) -c1cccc2ncc (nc12) -c1cnn (c1) C1CCNCC1
Molecular Formula
C27H28F2N6O·2HCl
Molecular Weight
563.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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