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WP-1130

Degrasyn (WP1130) is a small molecule inhibitor that targets specific deubiquitinases (DUBs) including USP5 and USP9x, and also inhibits Bcr-Abl and JAK2-STAT signaling. It is utilized in research to study protein degradation pathways and oncogenic signaling in both cellular and animal models of cancer and inflammation.

Product Specifications

CAS Number

856243-80-6

Product Name Alternative

Degrasyn

Field of Research

Cell Biology, Protein Biochemistry

Purity

>98%

Bioactivity

DUB inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 45 mg/ml), or in Ethanol (up to 25 mg/ml) .

Smiles

CCC[C@H] (NC (=O) C (=C\c1cccc (Br) n1) \C#N) c1ccccc1

Molecular Formula

C19H18BrN3O

Molecular Weight

384.28

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S, E) -3- (6-bromopyridin-2-yl) -2-cyano-N- (1-phenylbutyl) acrylamide

Available Sizes

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