CCT128930 hydrochloride
CCT128930 hydrochloride is a potent and selective AKT inhibitor (IC50 = 6 nM) that induces cell cycle arrest, DNA damage, and autophagy. It demonstrates significant selectivity over PKA and p70S6K. This compound is a valuable research tool for studying AKT signaling in cancer biology, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2453324-32-6
Product Name Alternative
PTEN, selective, Protein kinase B, PKB, PKA, phosphorylation, U87MG, Akt2, Akt, BT474, Apoptosis, Autophagy, arrest, cell, breast cancer, CCT128930, CCT 128930, CCT 128930 Hydrochloride, CCT-128930, CCT128930 hydrochloride, CCT128930 Hydrochloride, CCT-128930 Hydrochloride, CCT-128930 hydrochloride, CCT128930 hydrochloride (885499-61-6 Free base), DNA damage, cycle, inhibit, p70S6K, glioblastoma, growth, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
98.55% (May vary between batches)
Solubility
DMSO:55 mg/mL (145.39 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.29 mM)
Smiles
Cl.NC1 (Cc2ccc (Cl) cc2) CCN (CC1) c1ncnc2[nH]ccc12
Molecular Formula
C18H21Cl2N5
Molecular Weight
378.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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