AZ960
AZ960 is a potent and selective ATP-competitive inhibitor of JAK2, demonstrating high inhibitory activity with an IC50 of less than 3 nM and a Ki of 0.45 nM. It is a valuable research tool for studying JAK-STAT signaling in hematological malignancies and myeloproliferative disorders, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
905586-69-8
Product Name Alternative
Apoptosis, AZ 960, AZ960, AZ-960, inhibit, JAK, JAK2, Janus kinase, Parasite, Inhibitor, VirusProtease, Virus Protease
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology
Purity
96.02% (May vary between batches)
Solubility
Smiles
C[C@H] (Nc1nc (Nc2cc (C) [nH]n2) c (F) cc1C#N) c1ccc (F) cc1
Molecular Formula
C18H16F2N6
Molecular Weight
354.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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