AZ960

AZ960 is a potent and selective ATP-competitive inhibitor of JAK2, demonstrating high inhibitory activity with an IC50 of less than 3 nM and a Ki of 0.45 nM. It is a valuable research tool for studying JAK-STAT signaling in hematological malignancies and myeloproliferative disorders, with utility in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

905586-69-8

Product Name Alternative

Apoptosis, AZ 960, AZ960, AZ-960, inhibit, JAK, JAK2, Janus kinase, Parasite, Inhibitor, VirusProtease, Virus Protease

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Purity

96.02% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:55 mg/mL (155.21 mM) ; Ethanol:3 mg/mL (8.47 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.64 mM)