GW3965 HCl
GW3965 HCl is a potent and selective agonist of liver X receptors α and β (LXRα/β), exhibiting EC50 values of 190 nM and 30 nM, respectively. This compound is widely used in research to investigate LXR pathways in lipid metabolism, inflammation, and atherosclerosis, employing both in vitro and in vivo experimental models.
Product Specifications
CAS Number
405911-17-3
Product Name Alternative
HLXRα, hLXRβ, GW 3965, GW 3965 Hydrochloride, GW3965, GW-3965, GW3965 HCl, GW3965 Hydrochloride, GW3965 hydrochloride, GW-3965 hydrochloride, GW-3965 Hydrochloride, inhibit, Inhibitor, LXR, LXRα/SRC1 LiSA, LiverXReceptor, Liver X Receptor, Liver X receptor
Field of Research
Neuroscience
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 48 mg/ml)
Smiles
C1ccc (cc1) C (CN (CCCOc1cccc (c1) CC (=O) O) Cc1c (c (ccc1) C (F) (F) F) Cl) c1ccccc1.Cl
Molecular Formula
C33H31ClF3NO3 • HCl
Molecular Weight
618.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[3-[[[2-Chloro-3- (trifluoromethyl) phenyl]methyl] (2,2-diphenylethyl) amino]propoxy]-benzeneacetic acid, hydrochloride
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