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GW3965 HCl

GW3965 HCl is a potent and selective agonist of liver X receptors α and β (LXRα/β), exhibiting EC50 values of 190 nM and 30 nM, respectively. This compound is widely used in research to investigate LXR pathways in lipid metabolism, inflammation, and atherosclerosis, employing both in vitro and in vivo experimental models.

Product Specifications

CAS Number

405911-17-3

Product Name Alternative

HLXRα, hLXRβ, GW 3965, GW 3965 Hydrochloride, GW3965, GW-3965, GW3965 HCl, GW3965 Hydrochloride, GW3965 hydrochloride, GW-3965 hydrochloride, GW-3965 Hydrochloride, inhibit, Inhibitor, LXR, LXRα/SRC1 LiSA, LiverXReceptor, Liver X Receptor, Liver X receptor

Field of Research

Neuroscience

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 48 mg/ml)

Smiles

C1ccc (cc1) C (CN (CCCOc1cccc (c1) CC (=O) O) Cc1c (c (ccc1) C (F) (F) F) Cl) c1ccccc1.Cl

Molecular Formula

C33H31ClF3NO3 • HCl

Molecular Weight

618.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3-[3-[[[2-Chloro-3- (trifluoromethyl) phenyl]methyl] (2,2-diphenylethyl) amino]propoxy]-benzeneacetic acid, hydrochloride

Available Sizes

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