What is the catalog number for Bafetinib?

The catalog number for Bafetinib is orb1300879.

What sizes are available for Bafetinib?

Bafetinib is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does Bafetinib come in?

Bafetinib is available in 9 different pack sizes.

Is Bafetinib in stock?

Bafetinib is currently made to order / not held in immediate stock. Contact us for lead time.

Bafetinib

Bafetinib (INNO-406) is a potent and selective dual inhibitor of Bcr-Abl and Lyn kinases, with IC50 values of 5.8 nM and 19 nM, respectively. It shows minimal activity against c-Kit and PDGFR and is ineffective against the T315I mutant. This compound is used in research for chronic myeloid leukemia, demonstrating efficacy in both cellular and animal models of the disease.

Product Specifications

CAS Number

859212-16-1

Product Name Alternative

INNO 406, INNO406, INNO-406, Inhibitor, NS187, NS-187, NS 187, inhibit, mutations, Lyn, Abl, Autophagy, Apoptosis, Bafetinib, BcrAbl, Bcr-Abl, philadelphia chromosome-positive leukemias, Src

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

94.16% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.72 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:120 mg/mL (208.11 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)