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MLN8054

MLN8054 is a highly selective small molecule inhibitor of Aurora A kinase, exhibiting potent activity with an IC50 of 4 nM. It is a valuable research tool for studying mitotic progression and has been utilized in both in vitro cellular assays and in vivo xenograft models to investigate oncology and cell cycle biology.

Product Specifications

CAS Number

869363-13-3

Product Name Alternative

PKA, Inhibitor, Lck, inhibit, MLN 8054, MLN8054, MLN-8054, CaseinKinase, Casein Kinase, CK2, Aurora A, Aurora B, Aurora Kinase, AuroraKinase

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.07% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:88 mg/mL (184.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.92 mM)

Smiles

OC (=O) c1ccc (Nc2ncc3CN=C (c4cc (Cl) ccc4-c3n2) c2c (F) cccc2F) cc1

Molecular Formula

C25H15ClF2N4O2

Molecular Weight

476.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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