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Tofacitinib

Tofacitinib (Tasocitinib) is an orally bioavailable Janus kinase (JAK) inhibitor with selectivity for JAK3, JAK2, and JAK1. It is a research compound applied in studies of rheumatoid arthritis and other immune-mediated diseases, utilizing both in vitro cellular assays and in vivo animal models to investigate JAK-STAT signaling pathways.

Product Specifications

CAS Number

477600-75-2

Product Name Alternative

Tasocitinib; CP-690550

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

JAK inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml) .

Smiles

C[C@@H]1CCN (C[C@@H]1N (C) C1=C2C=CNC2=NC=N1) C (=O) CC#N

Molecular Formula

C16H20N6O

Molecular Weight

312.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(3R,4R) -4-Methyl-3- (methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino) -β-oxo-1-piperidine-propanenitrile

Available Sizes

Frequently Asked Questions

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