BMS-345541
BMS-345541 (IKK Inhibitor III) is a selective small molecule inhibitor targeting IKK-2 and IKK-1 catalytic subunits with IC50 values of 0.3 μM and 4 μM, respectively. It is widely used in vitro and in vivo to study NF-κB signaling in inflammation, cancer, and immune response research.
Product Specifications
CAS Number
445430-58-0
Product Name Alternative
BMS345541, BMS-345541, BMS-345541 free base, BMS 345541, IκB kinase, IκB, I kappa B kinase, IKK2, IkB/IKK, IkB, IKK Inhibitor III, IKK1, IKK
Field of Research
Signal Transduction
Purity
98.74% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.92 mM) ; DMSO:5.1 mg/mL (19.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cnc2c (NCCN) nc3ccc (C) cc3n12
Molecular Formula
C14H17N5
Molecular Weight
255.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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