Tubacin
Tubacin is a potent, reversible, and cell-permeable small molecule that selectively inhibits HDAC6 with a 4 nM IC50, showing ~350-fold selectivity against HDAC1. It is widely used in vitro and in vivo to study HDAC6's role in oncology, neurology, and immunology, particularly in processes involving protein aggregation and cell motility.
Product Specifications
CAS Number
537049-40-4
Product Name Alternative
Inhibit, Inhibitor, HDAC, HDAC6, Histone deacetylases, VirusProtease, Virus Protease, Tubacin
Field of Research
Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology
Purity
95.63% (May vary between batches)
Solubility
H2O:<1 mg/mL; DMSO:50 mg/mL (69.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.57 mM) ; Ethanol:<1 mg/mL
Smiles
S (C[C@@H]1O[C@@H] (O[C@@H] (C1) C2=CC=C (CO) C=C2) C3=CC=C (NC (CCCCCCC (NO) =O) =O) C=C3) C4=NC (=C (O4) C5=CC=CC=C5) C6=CC=CC=C6
Molecular Formula
C41H43N3O7S
Molecular Weight
721.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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