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Tubacin

Tubacin is a potent, reversible, and cell-permeable small molecule that selectively inhibits HDAC6 with a 4 nM IC50, showing ~350-fold selectivity against HDAC1. It is widely used in vitro and in vivo to study HDAC6's role in oncology, neurology, and immunology, particularly in processes involving protein aggregation and cell motility.

Product Specifications

CAS Number

537049-40-4

Product Name Alternative

Inhibit, Inhibitor, HDAC, HDAC6, Histone deacetylases, VirusProtease, Virus Protease, Tubacin

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology

Purity

95.63% (May vary between batches)

Solubility

H2O:<1 mg/mL; DMSO:50 mg/mL (69.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.57 mM) ; Ethanol:<1 mg/mL

Smiles

S (C[C@@H]1O[C@@H] (O[C@@H] (C1) C2=CC=C (CO) C=C2) C3=CC=C (NC (CCCCCCC (NO) =O) =O) C=C3) C4=NC (=C (O4) C5=CC=CC=C5) C6=CC=CC=C6

Molecular Formula

C41H43N3O7S

Molecular Weight

721.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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