What is the catalog number for Desmethyl Erlotinib?

The catalog number for Desmethyl Erlotinib is orb1300865.

What sizes are available for Desmethyl Erlotinib?

Desmethyl Erlotinib is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Desmethyl Erlotinib come in?

Desmethyl Erlotinib is available in 8 different pack sizes.

Is Desmethyl Erlotinib in stock?

Desmethyl Erlotinib is currently made to order / not held in immediate stock. Contact us for lead time.

Desmethyl Erlotinib

Desmethyl Erlotinib (CP-473420) is the primary active metabolite of the EGFR inhibitor Erlotinib. It exhibits potent inhibitory activity against EGFR with an IC50 of 2 nM, making it a valuable reference compound for studying drug metabolism and efficacy in cancer research, both in vitro and in vivo.

Product Specifications

CAS Number

183321-86-0

Product Name Alternative

Desmethyl Erlotinib, DrugMetabolite, Drug Metabolite, CP 473420, CP 373420, CP473420, CP-473420, CP373420, CP-373420, EGFR, inhibit, Inhibitor, O-Desmethyl Erlotinib, OSI 420, OSI420, OSI-420

Field of Research

Cardiovascular Research, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.92% (May vary between batches)

Solubility

DMSO:83 mg/mL (218.76 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.7 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)