MM-102
MM-102 is a potent small molecule inhibitor of the WDR5-MLL interaction with sub-nanomolar affinity. It selectively impedes proliferation and triggers apoptosis in MLL-rearranged leukemia cells in vitro, serving as a critical chemical probe for epigenetic and cancer research.
Product Specifications
CAS Number
1417329-24-8
Product Name Alternative
Inhibit, MM 102, MM102, MM-102, MLL1, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, HMTase Inhibitor IX
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:140 mg/mL (209.02 mM) ; H2O:92 mg/mL (137.35 mM) ; Ethanol:93 mg/mL (138.85 mM)
Smiles
C (NC (C1=CC=C (F) C=C1) C2=CC=C (F) C=C2) (=O) C3 (NC ([C@@H] (NC (C (NC (C (C) C) =O) (CC) CC) =O) CCCNC (=N) N) =O) CCCC3
Molecular Formula
C35H49F2N7O4
Molecular Weight
669.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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