Ridaforolimus

Ridaforolimus is a non-prodrug rapamycin analog that acts as a potent and selective mTOR kinase inhibitor. It is used in cancer research to study proliferation and survival pathways, with applications in both in vitro cell-based assays and in vivo tumor models.

Product Specifications

CAS Number

572924-54-0

Product Name Alternative

Ridaforolimus, MK8669, MK-8669, MK 8669, inhibit, mTOR, Mammalian target of Rapamycin, Inhibitor, AP 23573, AP23573, AP-23573, Autophagy, Deforolimus

Field of Research

Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction

Purity

90.00% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:182 mg/mL (183.8 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.04 mM)

Smiles

[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (CC (=O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@@H] (OP (C) (C) =O) [C@@H] (C1) OC