What is the catalog number for PHA-680632?

The catalog number for PHA-680632 is orb1300855.

What sizes are available for PHA-680632?

PHA-680632 is available in the following size(s): 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does PHA-680632 come in?

PHA-680632 is available in 6 different pack sizes.

Is PHA-680632 in stock?

PHA-680632 is currently made to order / not held in immediate stock. Contact us for lead time.

PHA-680632

PHA-680632 is a potent, pan-Aurora kinase inhibitor with IC50 values of 27 nM (Aurora A), 135 nM (Aurora B), and 120 nM (Aurora C) . It demonstrates high selectivity, showing 10- to 200-fold less potency against kinases such as FGFR1 and VEGFR2/3. This inhibitor is a valuable chemical probe for studying mitotic progression and cell cycle dysregulation in both cellular and animal cancer models.

Product Specifications

CAS Number

398493-79-3

Product Name Alternative

AuroraKinase, Aurora Kinase, Aurora C, Aurora A, Aurora B, Inhibitor, FGFR1, inhibit, PHA 680632, PHA680632, PHA-680632, PLK1

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction

Purity

98.20% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.58 mM) ; DMSO:93 mg/mL (185.4 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)