AG14361

AG14361 is a potent small molecule inhibitor of PARP1, exhibiting a Ki value below 5 nM. This compound is a valuable research tool for studying DNA repair mechanisms in vitro and has been utilized in preclinical cancer research models to investigate synthetic lethality and combination therapies.

Product Specifications

CAS Number

328543-09-5

Product Name Alternative

AG 14361, AG14361, AG-14361, PARP, PARP1, inhibit, Inhibitor, poly ADP ribose polymerase

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

97.65% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:15 mg/mL (46.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.12 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)