AG14361
AG14361 is a potent small molecule inhibitor of PARP1, exhibiting a Ki value below 5 nM. This compound is a valuable research tool for studying DNA repair mechanisms in vitro and has been utilized in preclinical cancer research models to investigate synthetic lethality and combination therapies.
Product Specifications
CAS Number
328543-09-5
Product Name Alternative
AG 14361, AG14361, AG-14361, PARP, PARP1, inhibit, Inhibitor, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.65% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:15 mg/mL (46.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.12 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CN (C) Cc1ccc (cc1) -c1nc2cccc3C (=O) NCCn1c23
Molecular Formula
C19H20N4O
Molecular Weight
320.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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