Domatinostat
Domatinostat (4SC202) is a selective class I HDAC inhibitor targeting HDAC1, HDAC2, and HDAC3, and also inhibits LSD1. It has been investigated in Phase 1 clinical trials for oncology research, with studies demonstrating its activity in both in vitro cellular assays and in vivo cancer models.
Product Specifications
CAS Number
910462-43-0
Product Name Alternative
Domatinostat, 4SC202, 4SC-202, 4SC-202 (free base), 4SC 202, Apoptosis, inhibit, Histone deacetylases, Inhibitor, HDAC, HDAC3, HDAC5, HDAC2, HDAC1, HDAC11
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.56% (May vary between batches)
Solubility
DMSO:82 mg/mL (183.24 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.37 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cn1cc (cn1) -c1ccc (cc1) S (=O) (=O) n1ccc (\C=C\C (=O) Nc2ccccc2N) c1
Molecular Formula
C23H21N5O3S
Molecular Weight
447.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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