4μ8C
4μ8C is a potent and selective inhibitor of IRE1's RNase activity, exhibiting an IC50 of 76 nM. This small molecule is widely used in vitro to study the unfolded protein response (UPR) in cellular models of endoplasmic reticulum stress and related diseases.
Product Specifications
CAS Number
14003-96-4
Product Name Alternative
Inhibit, Inhibitor, IRE1, IRE1 Inhibitor III, IRE1 Rnase, Inositol requiring enzyme 1, 4mu8C, 4μ8C
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
IRE1 ribonuclease inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
Cc1cc (=O) oc2c (C=O) c (O) ccc12
Molecular Formula
C11H8O4
Molecular Weight
204.18
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
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