A-966492
A-966492 is a potent and novel small molecule inhibitor of PARP1 (Ki=1 nM) and PARP2 (Ki=1.5 nM) . It is widely used in cancer research, particularly in studies of DNA damage repair, both in vitro and in preclinical in vivo models for evaluating synthetic lethality.
Product Specifications
CAS Number
934162-61-5
Product Name Alternative
A966492, A-966492, A 966492, PARP2, PARP1, PARP, inhibit, Inhibitor, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.08 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:8.13 mg/mL (25.07 mM)
Smiles
NC (=O) c1cccc2[nH]c (nc12) -c1ccc (cc1F) [C@@H]1CCCN1
Molecular Formula
C18H17FN4O
Molecular Weight
324.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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