AMG 517
AMG 517 is a potent and selective TRPV1 antagonist, effectively inhibiting proton, capsaicin, and heat-induced channel activation with low nanomolar IC50 values. It is a valuable research tool for studying pain, inflammation, and thermoregulation in both in vitro assays and in vivo models.
Product Specifications
CAS Number
659730-32-2
Product Name Alternative
Transient receptor potential channels, TRPV1, TRPV Channel, TRPVChannel, TRPChannel, TRP Channel, AMG 517, AMG517, AMG-517, Inhibitor, inhibit
Field of Research
Pharmacology & Drug Discovery
Purity
99.66% (May vary between batches)
Solubility
DMSO:43 mg/mL (99.91 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.65 mM)
Smiles
O (C1=C2C (SC (NC (C) =O) =N2) =CC=C1) C=3C=C (N=CN3) C4=CC=C (C (F) (F) F) C=C4
Molecular Formula
C20H13F3N4O2S
Molecular Weight
430.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Eukaryotic Interleukin 7 Receptor (IL7R), Recombinant, Human, His-Tag
Eukaryotic Interleukin 7 Receptor (IL7R), Recombinant, Human, His-Tag
Eukaryotic Interleukin 7 Receptor (IL7R), Recombinant, Human, His-Tag
Eukaryotic Interleukin 7 Receptor (IL7R), Recombinant, Human, His-Tag
![Rabbit Polyclonal CKIP-1 Antibody [Alexa Fluor 350]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
Rabbit Polyclonal CKIP-1 Antibody [Alexa Fluor 350]
