BV02
BV02 is a small molecule inhibitor of 14-3-3 protein-protein interactions. It is used in chronic myeloid leukemia research to disrupt cells harboring both wild-type and therapy-resistant T315I Bcr-Abl mutations, as demonstrated in various cellular studies.
Product Specifications
CAS Number
292870-53-2
Product Name Alternative
14-3-3 protein-protein interaction, 2- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) -1,3-dioxoisoindoline-5-carboxylic acid, BV 02, BV02, BV-02
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry, Signal Transduction
Purity
99.79% (May vary between batches)
Solubility
DMSO:10 mg/mL (26.5 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.65 mM)
Smiles
Cc1c (N2C (=O) c3ccc (cc3C2=O) C (O) =O) c (=O) n (-c2ccccc2) n1C
Molecular Formula
C20H15N3O5
Molecular Weight
377.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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