(R) -MMP408
This small molecule is a potent and selective MMP-12 inhibitor, exhibiting IC50 values of 2, 160, 320, and 22.3 nM against the human, mouse, rat, and sheep enzymes, respectively. It is a valuable research tool for studying the role of MMP-12 in inflammatory and fibrotic diseases in both cellular assays and animal models.
Product Specifications
CAS Number
1258003-93-8
Product Name Alternative
MMP-408, MMP-12, MMP-12 Inhibitor, MMP 12, MMP 408
Field of Research
Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Protein Biochemistry
Purity
97.51% (May vary between batches)
Solubility
DMSO:50 mg/mL (118.92 mM)
Smiles
N (C (OC) =O) C=1C=C2C=3C (OC2=CC1) =CC (S (N[C@H] (C (C) C) C (O) =O) (=O) =O) =CC3
Molecular Formula
C19H20N2O7S
Molecular Weight
420.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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