Idarubicin hydrochloride
Idarubicin hydrochloride, sold as Zavedos, is the hydrochloride salt form of the anthracycline Idarubicin. It functions as a DNA topoisomerase II inhibitor, exhibiting potent activity against MCF-7 breast cancer cells with an IC50 of 3.3 ng/mL. This compound is widely used in cancer research for in vitro cytotoxicity studies and in vivo models of leukemia and solid tumors.
Product Specifications
CAS Number
57852-57-0
Product Name Alternative
Topoisomerase, Topo II (MCF-7 cells), Zavedos, Bacterial, Antibiotic, Autophagy, 4-Demethoxydaunorubicin, 4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl, 4-Demethoxydaunorubicin hydrochloride, 4-Demethoxydaunorubicin Hydrochloride, c-Myc, breast tumor, DNA/RNA Synthesis, DNA synthesis, inhibit, Myc, Fungal, Idamycin, Idarubicin, Idarubicin HCl, Idarubicin Hydrochloride, Idarubicin hydrochloride, Inhibitor, leukaemias, MCF-7
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.91% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:255 mg/mL (477.57 mM) ; H2O:5 mg/mL (9.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.18 mM)
Smiles
Cl.C[C@@H]1O[C@H] (C[C@H] (N) [C@@H]1O) O[C@H]1C[C@@] (O) (Cc2c (O) c3C (=O) c4ccccc4C (=O) c3c (O) c12) C (C) =O
Molecular Formula
C26H27NO9·HCl
Molecular Weight
533.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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