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SAR131675

SAR131675 is a selective small molecule inhibitor of VEGFR3 (FLT4) with a reported IC50 of 23 nM. It is a valuable research tool for studying lymphangiogenesis in both cellular assays and animal models, particularly in oncology and vascular biology research.

Product Specifications

CAS Number

1433953-83-3

Product Name Alternative

Inhibitor, inhibit, Vascular endothelial growth factor receptor, VEGFR3, VEGFR, SAR 131675, SAR131675, SAR-131675

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.52% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.58 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:70 mg/mL (195.32 mM)

Smiles

C (C) N1C=2C (C (=O) C (C (NC) =O) =C1N) =CC=C (C#C[C@@] (COC) (C) O) N2

Molecular Formula

C18H22N4O4

Molecular Weight

358.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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